Hi,

That is quite unusual.

When this occurs, are your Processor Load indicators in green?

A high processor load could cause dropping frames, which might lead to missed key presses.

Additionally, do you have multiple keyboards connected, and are all of them visible in Edit -> Preferences under Keyboard Devices? Even when the assigned keys no longer work?

You might also want to try turning off the "Only active when application is focused" setting there.

Lastly, check whether the assigned keys appear in File -> Properties under Keyboard Assignments when they stop working:

Warmest regards,

Even without load on the processor. I checked all the settings are as you showed, but still sometimes disappears

Hi,

If you haven't already, try turning off the "Only active when application is focused" setting:

Additionally, when the assigned keyboard shortcuts stop working, do the built-in shortcuts, such as CTRL + P (brings up the Preferences window), continue to function?
Are you able to assign a new keyboard key, or does the Assign Keyboard Controller window fail to detect any key presses at that point?

Warmest regards,